To multiply a 2 digit number by a 2 digit number, Write down the problem. Multiply the number in the ones place of the bottom number by both digits of the top number. Write a “0” in the units column below the first product. Multiply the number in the tens place of the bottom number by both digits of the top number. Add up the two products. Learn about multiplication of 2 digit numbers with the help of resources on this page.